Prof. Wei Yutuo, Ph.D., Doctoral and Master Supervisor
Contact
weiyutuo@gxu.edu.cn
Biography
Guangxi, Guigang City; From September 1990 to July 1994, majored in Plant Genetics and Breeding, Southwest Agricultural University; from September 1996 to July 1999, studied for a master's degree in crop Genetics and Breeding, majoring in biotechnology, Southwest Agricultural University; obtained the master's degree in 1999, and was assigned to Guangxi University for microbiology research in the same year. In 2001, he began to study for a doctor's degree in Microbiology and obtained his doctorate degree in December 2004.
Teaching and research achievements
I am mainly engaged in research and application of microbial biotechnology and industrial enzyme development. I have achieved certain research results in the development and application of new amylases and the biological conversion and utilization of starch. By using biological transformation of cassava starch to produce algae sugar, I have made China the second country in the world to have independent intellectual property rights and industrial production capacity of algae sugar. Additionally, I have made China the first country to achieve large-scale production of algae sugar using cassava starch. I am also leading in the cloning, molecular modification, and high-efficiency expression of algae sugar synthase gene in China.
In the field of anaerobic digestion, I have researched and developed a new type of biogas digester that eliminates crust formation, allowing for better mechanical automation and continuous production of biogas. I have served as editorial committee member and guest editor for international journals, published over 80 academic papers, obtained 5 patents, and won one first prize in Guangxi Natural Science Award.
In terms of teaching, I have taught courses such as Principles of Genetic Engineering, Crop Breeding, Production Internship, Graduation Internship, Innovation Practice, and supervised undergraduate thesis. I have also taught 6 postgraduate courses. I have won a first prize in school-level teaching achievement awards, a second prize in autonomous regional-level teaching achievement awards, and the title of "My Favorite Teacher" at Guangxi University. I independently edited a textbook titled "Principles and Techniques of Genetic Engineering."
Main research projects presided over
1. Hosted the National Nature Foundation: Construction of efficient lignocellulosic digestive system based on direct interspecific electron transfer and research on key electroactive microorganisms, execution period: 2023.01-2026.12
2. Hosted the National Natural Foundation of China: Research on Key amino acid residues specific to trehalose synthase substrates; Execution period: 2015.01-2018.12
3. Presided over the National Natural Foundation of China: Research on the molecular structure basis of salophilic α-amylase salt adaptability of Escherichia coli, executive year: January 2012 - December 2015
4. Presided over the project of Guangxi Scientific Research and Technology Development Plan: Gene cloning and molecular modification of novel alpha-amylase, execution period: 2017.01-2020.12
5. Presided over Guangxi Scientific Research and Technology Development Plan Project: Research on the key technology of bio-conversion of cassava starch to produce maltose oligosaccharide; Execution period: 2011.01-2013.12
6. Presided over the project of Guangxi Science Foundation: Construction of high-throughput screening system for sucrase and cloning of new sucrase gene in uncultured microorganisms; Executive year: 2006.05-2009.05
7. Presided over the project of Guangxi Natural Science Foundation: Molecular modification of trehalose synthase; Execution period: 2012.03-2015.02
8. Presided over the biomass comprehensive utilization technology development and platform construction project, execution period: January 2012 - December 2014;
9. Presided over the subproject of national "863" major project: Optimization of fermentation process of 1, 3-propylene glycol recombinant strain; Executive year: 2006.12-2010.12
10. Main cooperation project of National Natural Resources Foundation: Key scientific basis and practical technology of producing fuel ethanol by fermentation method with grass fiber as raw material; Execution period: 2007.01-2009.12
11. Mainly participated in the subproject of 973 project: molecular oriented evolution of trehalose synthase in thermophilic bacteria; Execution period: 2004.09-2009.08
Research direction
His research interests include construction of genetically engineered bacteria, development and research of biological products, molecular evolution of protease, microbial biotechnology and microbial engineering.
Representative papers
[1] Liang J., Huang R., Huang Y., Wang X., Du L., & Wei Y.*. Cloning, expression, properties, and functional amino acid residues of new trehalose synthase from Thermomonospora curvata DSM 43183. Journal of Molecular Catalysis B: Enzymatic, 2013, 90, 26–32.
[2] Wei Y., Wang X., Liang J., Li X., Du L., &Huang R. Identification of a halophilic α-amylase gene from Escherichia coli JM109 and characterization of the property recombinant enzyme. Biotechnology Letters, 2013, 35, 1061–1065.
[3] Wei Y., Liang J., Huang Y., Lei P., Du L., & Huang R. Simple, fast, and efficient process for producing and purifying trehalulose. Food Chemistry, 2013, 138(2-3), 1183-1188.
[4] Zhang Z., Lin L., Tang H., Zeng S., Guo Y., Wei Y.*, ... & Du L*. A convenient fluorescence-based assay for the detection of sucrose transport and the introduction of a sucrose transporter from potato into Clostridium Strains. Molecules, 2019, 24(19), 3495.
[5] Pan S., Wen C., Liu Q., Chi Y., Mi H., Li Z., ... & Wei Y.*. A novel hydraulic biogas digester controlling the scum formation in batch and semi-continuous tests using banana stems. Bioresource Technology, 2019, 286, 121372.
[6] Pan S. #, Yao T. #, Du L., &Wei Y.*. Site-saturation mutagenesis at amino acid 329 of Klebsiella pneumoniae halophilic alpha -amylase affects enzymatic properties. Journal of Bioscience and Bioengineering, 2020, 129 (2), 155–159.
[7] Pan S., Chi Y., Zhou L., Li Z., Du L., & Wei Y.*. Evaluation of squeezing pretreatment for improving methane production from fresh banana pseudo-stems. Waste Management, 202,102, 900-908.
[8] Liu Q., Pan S., Long Z., Li Z., Du L., & Wei Y.*. Assessment of fresh and dry rice straw for biogas potential by anaerobic digestion. BioEnergy Research, 2020, 13, 845-852.
[9] Pan S. #, Liu Q. #, Wen C., Li Z., Du L., & Wei Y.*. Producing biogas from rice straw: Kinetic analysis and microbial community dynamics. BioEnergy Research, 2021, 14, 1338–1348.
[10] Zhou L., Guo F., Pan S., Lu B., Du L., & Wei Y.*. Synergistic digestion of banana pseudo-stems with chicken manure to improve methane production: Semi-continuous manipulation and microbial community analysis. Bioresource Technology, 2021, 328, 124851.
[11] Pan S., Zabed H.M., Wei Y.*, & Qi X.*. Technoeconomic and environmental perspectives of biofuel production from sugarcane bagasse: Current status, challenges and future outlook. Industrial Crops & Products, 2022, 188, 115684.
[12] Liu Q., Pan S., Zhou L., Feng L., Li Z., Du L., & Wei Y.*. Improving the biogas potential of rice straw through microwave-assisted ammoniation pretreatment during anaerobic digestion. BioEnergy Research, 2022, 15, 1240–1250.
[13] Pan S., Zabed, H.M., Zhao M., Qi X.*, & Wei Y*. Techno-economic and life cycle assessments for bioenergy recovery from acid-hydrolyzed residues of sugarcane bagasse in the biobased xylose production platform. Journal of Cleaner Production. 2023, 400, 136718.
[14] Pan S., Wang G., Sun C., Du L., Qi X., &Wei Y.*. A novel maltooligosaccharide-forming α-amylase from Bacillus cereus and its application in the preparation of maltopentaose product. Process Biochemistry, 2023, 128, 68–75.
